Felipe Jiménez-Aspee, Ph.D.

UNDER CONSTRUCTION!


Education and professional experience


Publications 

27. Orqueda et al. 

26. Schmeda-Hirschmann et al.

25. Ávila et al.

24. Pino ramos et al.

23. Schmeda-Hirschmann et al.

22. Chamorro et al.

21. Thomas-Valdés et al.

20. Mieres-Castro et al.

19. Burgos-Edwards et al.

18. Theoduloz, C., Alzate-Morales, J., Jiménez-Aspee, F., Isla, M.I., Alberto, M.R., Pertino, M.W., Schmeda-Hirschmann, G. Inhibition of key enzymes in the inflammatory pathway by hybrid molecules of terpenes and synthetic drugs: in vitro and in silico studies. Accepted for printing in: Chemical Biology & Drug Design 93: 290-299.

17. Jiménez-Aspee, F.*, Theoduloz, C., Gómez-Alonso, S., Hermosín-Gutiérrez, I., Reyes, M., Schmeda-Hirschmann, G. (2018). Polyphenolic profile and antioxidant activity of meristem and leaves from “chagual” (Puya chilensis Mol.), a salad from central Chile. Food Research International 114: 90-96.

16. Theoduloz, C., Burgos-Edwards, A., Schmeda-Hirschmann, G., Jiménez-Aspee, F.* (2018): Polyphenols from wild Chilean currants (Ribes spp.) increase the activity of intracellular antioxidant enzymes in human gastric AGS cells. Food Bioscience 24: 80-88.

15. Burgos-Edwards, A., Jiménez-Aspee, F., Theoduloz, C., Schmeda-Hirschmann, G. (2018). Colonic fermentation of polyphenols from Chilean currants (Ribes spp.) and its effect on antioxidant capacity and metabolic syndrome-associated enzymes. Food Chemistry 258: 144-155.

14. Thomas-Valdés, S., Theoduloz, C., Jiménez-Aspee, F., Burgos-Edwards, A., Schmeda-Hirschmann, G. (2018): Changes in polyphenol composition and bioactivity of the native Chilean white strawberry (Fragaria chiloensis spp. chiloensis f. chiloensis) after in vitro gastrointestinal digestion. Food Research International 105: 10-18.

13. Jiménez-Aspee, F.*, Theoduloz, C., Soriano, M.D.P.C., Ugalde-Arbizu, M., Alberto, M.R., Zampini, I.C., Isla, M.I., Simirgiotis, M.J., Schmeda-Hirschmann, G. (2017): The native fruit Geoffroea decorticans from arid northern Chile: phenolic composition, antioxidant activities and in vitro inhibition of pro-inflammatory and metabolic syndrome-associated enzymes. Molecules 22: 1565.

12. Burgos-Edwards, A., Jiménez-Aspee, F.*, Thomas-Valdés, S., Schmeda-Hirschmann, G., Theoduloz, C. (2017): Qualitative and quantitative changes in polyphenol composition and bioactivity of Ribes magellanicum and R. punctatum after in vitro gastrointestinal digestion. Food Chemistry 237: 1073-1082.

11. Torres Carro, R., Isla, M.I., Thomas-Valdes, S., Jiménez-Aspee, F., Schmeda-Hirschmann, G., Alberto, M.R. (2017): Inhibition of pro-inflammatory enzymes by medicinal plants from the Argentinean highlands (Puna). Journal of Ethnopharmacology 205: 57-68.

10. Orqueda, M.E., Rivas, M., Zampini, I.C., Alberto, M.R., Torres, S., Cuello, S., Sayago, J., Thomas-Valdes, S., Jiménez-Aspee, F., Schmeda-Hirschmann, G., Isla, M.I. (2017): Chemical and functional characterization of seed, pulp and skin powder from chilto (Solanum betaceum), an Argentine native fruit. Phenolic fractions affect key enzymes involved in metabolic syndrome and oxidative stress. Food Chemistry 216: 70-79.

9. Jiménez-Aspee, F., Theoduloz, C., Vieira, M.N., Rodríguez-Werner, M.A., Schmalfuss, E., Winterhalter, P., Schmeda-Hirschmann, G. (2016): Phenolics from the Patagonian currants Ribes spp.: Isolation, characterization and cytoprotective effect in human AGS cells. Journal of Functional Foods 26: 11-26.

8. Jiménez-Aspée, F., Theoduloz, C., Ávila, F., Thomas-Valdés, S., Mardones, C., von Baer, D., Schmeda-Hirschmann, G. (2016): The Chilean wild raspberry (Rubus geoides Sm.) increases intracellular GSH content and protects against H2O2 and methylglyoxal-induced damage in AGS cells. Food Chemistry 194: 908-919.

7. Jiménez-Aspée, F., Thomas-Valdés, S., Schulz, A., Ladio, A.H., Theoduloz, C., Schmeda-Hirschmann, G. (2016): Antioxidant activity and phenolic profiles of the wild currant Ribes magellanicum from Chilean and Argentinean Patagonia. Food Science & Nutrition 4, 595-610.

6. Nina, N.V., Quispe, C., Jiménez-Aspee, F., Theoduloz, C., Giménez, A., Schmeda-Hirschmann, G. (2016): Chemical profiling and antioxidant activity of Bolivian propolis. Journal of the Science of Food and Agriculture 96, 2142-2153.

5. Nina, N., Quispe, C., Jiménez-Aspee, F., Theoduloz, C., Feresín, G.E., Lima, B., Leiva, E., Schmeda-Hirschmann, G. (2015): Antibacterial activity, antioxidant effect and chemical composition of propolis from the Region del Maule, central Chile. Molecules 20, 18144-18167.

4. Schmeda-Hirschmann, G., Quispe, C., Soriano, M.D.P.C., Theoduloz, C., Jiménez-Aspee, F., Perez, M.J., Cuello, A.S., Isla, M.I (2015): Chilean Prosopis mesocarp flour: phenolic profiling and antioxidant activity. Molecules. 20:7017-7033.

3. Jiménez-Aspee, F., Alberto, M.R., Quispe, C., Soriano, M.D.P.C., Theoduloz, C., Zampini, I.C., Isla, M.I., Schmeda-Hirschmann, G. (2015): Anti-inflammatory activity of Copao (Eulychnia acida Phil., Cactaceae) fruits. Plant Foods for Human Nutrition. 70: 135-140.

2. Jiménez-Aspee, F., Quispe, C., Soriano, M.D.P.C., Fuentes-Gonzalez, J., Hüneke, E., Theoduloz, C., Schmeda-Hirschmann, G. (2014): Antioxidant activity and characterization of constituents in copao fruits (Eulychnia acida Phil., Cactaceae) by HPLC–DAD–MS/MSn. Food Research International. 62: 286-298.

1. Cortes, M.P., Álvarez, R., Sepúlveda, E., Jiménez-Aspee, F., Astudillo, L., Vallejos, G., Gutiérrez, M. (2014). A new isoxazolic compound act as a7 nicotinic receptor agonist in human umbilical vein endothelial cells. Zeitschrift fur Naturforschung, 69c, 291-299.

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