Education
June 2015 - Dr. rer. nat. (Ph.D.) in Nutritional Sciences, University of Hohenheim, Stuttgart, Germany
Thesis: The impact of vitamin E on xenobiotic metabolism and hepatic lipid accumulation
November 2011 - Diploma in Nutritional Sciences (equivalent to M.Sc.), University of Hohenheim, Stuttgart, Germany
Thesis: Development and partial validation of a high performance liquid chromatography(HPLC-ECD) method for the quantification of atorvastatin and metabolites.
Professional experience
Since 2021: Stand-in professor of Nutritional Sciences and Dietetics, University of Hohenheim, Stuttgart, Germany
2020 -2021: Assistant lecturer, Institute of Nutritional Sciences, University of Hohenheim, Stuttgart, Germany
2016 - 2020: Postdoctoral researcher at the National Institutes of Health, USA
December 2011 - December 2015: Doctoral student, Division Biofunctionality and Safety of Food, Institute of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
September 2012 - November 2012: Guest researcher, Institute of Chemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden
Awards and affiliations
2020 - GVF Vitamin Preis 2020
2016 - Professor Wild Award
2012 - Fellowship of the German Academic Exchange Service
Member of the Society of Nutrition and Food Science
Member of the American Society for Clinical Pharmacology and Therapeutics
Member of the Society for Free Radical Biology and Medicine
Publications
Original articles
Ma, Y., Karki, S., Brown, P. M., Lin, D. D., Podszun, M. C., Zhou, W., Belyaeva, O. V., Kedishvili, N. Y. & Rotman, Y. (2020)Characterization of essential domains in HSD17B13 for cellular localization and enzymatic activity. J Lipid Res 61: 1400-1409, IF 4.483.
Podszun, M. C., Alawad, A. S., Lingala, S., Morris, N., Huang, W. A., Yang, S., Schoenfeld, M., Rolt, A., Ouwerkerk, R., Valdez, K., Umarova, R., Ma, Y., Fatima, S. Z., Lin, D. D., Mahajan, L. S., Samala, N., Violet, P. C., Levine, M., Shamburek, R., Gharib, A. M., Kleiner, D. E., Garraffo, H. M., Cai, H., Walter, P. J. & Rotman, Y. (2020) Vitamin E treatment in NAFLD patients demonstrates that oxidative stress drives steatosis through upregulation of de-novo lipogenesis Redox Biol 37: 101710, IF 9.986.
Podszun M. C., Chung, J. Y., Ylaya, K., Kleiner, D. E., Hewitt, S. M. & Rotman, Y. (2020)4-HNE Immunohistochemistry and Image Analysis for Detection of Lipid Peroxidation in Human Liver Samples Using Vitamin E Treatment in NAFLD as a Proof of Concept. J Histochem Cytochem68: 635-643, IF 2.187.
Ma, Y., Brown, P. M., Lin, D. D., Ma, J., Feng, D., Belyaeva, O. .V, Podszun, M. C., Roszik, J., Allen, J., Umarova, R., Kleiner, D. E., Kedishvili, N. Y., Gavrilova, O., Gao, B. & Rotman, Y. (2020)Hsd17b13 Deficiency Does not Protect Mice From Obesogenic Diet Injury. Hepatology (published online), IF 14.679.
Suresh, R.R., Jain, S., Chen, Z., Tosh, D.K., Ma, Y., Podszun, M. C., Rotman, Y., Salvemini, D. & Jacobson, K.A. (2020)Design and in vivo activity of A 3 adenosine receptor agonist prodrugs. Purinergic Signal 16: 367-377, IF 3.065.
Anaya, K., Podszun, M.,Gadelha, C., Franco, O. L. &Frank, J.(2020)The coconut water antimicrobial peptide CnAMP1 is taken up into intestinal cells but does not alter P-glycoprotein expression and activity. Plant Foods for Human Nutrition 75: 396-403, IF 2.598.
Irías-Mata, A., Sus, N., Flory, S., Stock, D.,Woerner, D., Podszun, M. &Frank, J.(2018)α-Tocopherol transfer protein does not regulate the cellular uptake and intracellular distribution of α- and γ-tocopherols and -tocotrienols in cultured liver cells. Redox Biology 19: 28-36, IF 7.793.
Podszun, M. C., Jakobi, M., Birringer, M., Weiss, J. & Frank, J. (2016).The long chain α–tocopherol metabolite α-13’-COOH and γ-tocotrienol induce P-glycoprotein expression and activity by activation of the pregnane X receptor in the intestinal cell line LS 180. Mol Nutr Food Res, IF 4.551.
Podszun, M. C., Grebenstein, N., Spruss, A., Schlueter, T., Kremoser, C., Bergheim, I., &Frank, J.(2014).Dietary α-tocopherol and atorvastatin reduce high-fat-induced lipid-accumulation and down-regulate CD36 protein in the liver of guinea pigs. J Nutr Biochem 25: 573-579, IF 4.592.
Podszun, M. C., Grebenstein, N., Hofmann, U., &Frank, J.(2013). High-dose supplementation with natural α-tocopherol does neither alter the pharmacodynamics of atorvastatin nor its phase I metabolism in guinea pigs. Toxicology and Applied Pharmacology 266: 452-458,IF 4.447.
Review articles
Frank, J., Kisters, K., Stirban, O. A., Obeid, R., Lorkowski, S., Wallert, M., Egert, S., Podszun, M. C., Eckert, G. P., Pettersen, J. A., Venturelli, S., Classen, H. G. & Golombek, J. (2021)The role of biofactors in the prevention and treatment of age-related diseases. BioFactors, IF 6.113.
Podszun, M.C. &Frank, J.(2021) Impact of vitamin E on redox biomarkers in non-alcoholic fatty liver disease. Redox Biology 42: 101937, IF 11.799.
Podszun, M. C. &Frank, J.(2014)Vitamin E-drug interactions - molecular basis and clinical relevance. Nutr Res Rev 27: 215-231, IF 3.861.
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